Dpto. Fisiología, Genética y Microbiología. Pabellón 12
Universidad de Alicante
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Univeristy of Alicante
Ministerio de Generalitat Valenciana
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Cyanobacteria are a compact group of great ecological and biotechnological interest. We are using the unicellular cyanobacterium Synechococcus elongatus PCC 7942 as a model system in the following research lines:
Line 1
The cyanobacterial nitrogen interaction network
  A complex network of protein interactions allows cyanobacteria to control nitrogen metabolism in response to the intracellular nitrogen to carbon balance. PipX, a protein identified by us, is a multifunctional protein that forms complexes with the two nitrogen regulators PII and NtcA according to the 2-oxoglutarate levels. We are studying the molecular details and consequences of the complex protein interaction network in which these protein work.
Schematic model of the proposed mode of action of PipX
(adapted from Espinosa et. al., 2006).
  Structures of PII-PipX and NtcA-PipX complexes
(modified from Llacer et. al., 2010)

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